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1

Probing Ion Binding Sites in the Na+/Ca2+ Exchanger

MUNEKAZU SHIGEKAWA, TAKAHIRO IWAMOTO, AKIRA UEHARA, SATOMI KITA

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 4.01 MB

2002

2

Time-dependent changes in Ca release from EGTA-treated sarcoplasmic reticulum

Arnold M. Katz, Gary W. Fudyma, Doris I. Repke, Priscilla A. Nash, Munekazu Shigekawa

Journal:

The American Journal of Cardiology

Year:

1978

Language:

english

File:

PDF, 156 KB

english, 1978

3

Unique topology of the internal repeats in the cardiac Na+/Ca2+ exchanger

Takahiro Iwamoto, Tomoe Y Nakamura, Yan Pan, Akira Uehara, Issei Imanaga, Munekazu Shigekawa

Journal:

Year:

1999

Language:

english

File:

PDF, 344 KB

english, 1999

4

Effects of amiodarone on mutant Na+/Ca2+ exchangers expressed in CCL 39 cells

Yasuhide Watanabe, Takahiro Iwamoto, Isao Matsuoka, Tomoyuki Ono, Munekazu Shigekawa, Junko Kimura

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

5

Stimulatory and inhibitory effects of dimethylsulfoxide, propranolol and chlorpromazine on the partial reactions of ATPase of sarcoplasmic reticulum

Munekazu Shigekawa, Alfred A. Akowitz, Arnold M. Katz

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1979

Language:

english

File:

PDF, 897 KB

english, 1979

6

Myocyte damage in myopathic cell model

Yuko Iwata, Yuki Katanosaka, Zhu Shijun, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 243 KB

english, 2002

7

Phosphorylation and Modulation of the Na+-Ca2+ Exchanger in Vascular Smooth Muscle Cellsa

MUNEKAZU SHIGEKAWA, TAKAHIRO IWAMOTO, SHIGEO WAKABAYASHI

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 735 KB

english, 1996

8

Protein-protein interaction of detergent-solubilized Ca2+-ATPase during ATP hydrolysis analyzed by low-angel laser light scattering photometry coupled with high-performance gel chromatography

Yoshiyuki Kijima, Toshio Takagi, Munekazu Shigekawa, Michihiko Tada

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1990

Language:

english

File:

PDF, 839 KB

english, 1990

9

Doxorubicin directly binds to the cardiac-type ryanodine receptor

Kazuhiko Saeki, Ichiro Obi, Noriko Ogiku, Munekazu Shigekawa, Toshiaki Imagawa, Takeshi Matsumoto

Journal:

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

10

Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes

Koji Wakimoto, Hisako Fujimura, Takahiro Iwamoto, Toru Oka, Kinji Kobayashi, Satomi Kita, Sumiyo Kudoh, Makoto Kuro-o, Yo-ichi Nabeshima, Munekazu Shigekawa, Yuji Imai, Issei Komuro

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.45 MB

english, 2003

11

mRNA Expression and cDNA Sequences of .BETA.- and .GAMMA.-Sarcoglycans Are Normal in Cardiomyopathic Hamster Heart.

HANADA, Hironori, YOSHIDA, Tomokazu, PAN, Yan, IWATA, Yuko, NISHIMURA, Masahiko, SHIGEKAWA, Munekazu

Journal:

Biological & Pharmaceutical Bulletin

Year:

1997

File:

PDF, 965 KB

1997

12

Mechanisms of Reoxygenation-Induced Calcium Overload in Cardiac Myocytes: Dependence on pHi

Naruto Matsuda, Tohru Mori, Hiroshi Nakamura, Munekazu Shigekawa

Journal:

Journal of Surgical Research

Year:

1995

File:

PDF, 453 KB

1995

13

Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of substance P receptor

Martha Garcia, Kazuichi Sakamoto, Munekazu Shigekawa, Shigetada Nakanishi, Seiji Ito

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 669 KB

english, 1994

14

Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein

Yuko Kobayashi, Yuki Katanosaka, Yuko Iwata, Masayuki Matsuoka, Munekazu Shigekawa, Shigeo Wakabayashi

Journal:

Experimental Cell Research

Year:

2006

Language:

english

File:

PDF, 1.31 MB

english, 2006

15

A Novel Mechanism of Myocyte Degeneration Involving the Ca2+-Permeable Growth Factor-Regulated Channel

Yuko Iwata, Yuki Katanosaka, Yuji Arai, Kazuo Komamura, Kunio Miyatake and Munekazu Shigekawa

Journal:

The Journal of Cell Biology

Year:

2003

Language:

english

File:

PDF, 3.57 MB

english, 2003

16

Purification of cardiac (Na+,K+)-activated adenosine triphosphatase from rat

Takahide Watanabe, Yuko Tawada, Munekazu Shigekawa

Journal:

Analytical Biochemistry

Year:

1988

Language:

english

File:

PDF, 436 KB

english, 1988

17

Calmodulin-Binding Autoinhibitory Domain Controls “pH-Sensing” in the Na + /H + Exchanger NHE1 through Sequence-Specific Interaction †

Wakabayashi, Shigeo, Ikeda, Toshitaro, Iwamoto, Takahiro, Pouysségur, Jacques, Shigekawa, Munekazu

Journal:

Year:

1997

Language:

english

File:

PDF, 226 KB

english, 1997

18

Primary structure and functional expression from cDN A of the cardiac ryanodine receptor/calcium release channel

Junichi Nakai, Toshiaki Imagawa, Yasuhiro Hakamata, Munekazu Shigekawa, Hiroshi Takeshima, Shosaku Numa

Journal:

Year:

1990

Language:

english

File:

PDF, 1.24 MB

english, 1990

19

Inhibitory Effects of Guarana Seed Extract on Passive Cutaneous Anaphylaxis and Mast Cell Degranulation

JIPPO, Tomoko, KOBAYASHI, Yuko, SATO, Harumi, HATTORI, Atsushi, TAKEUCHI, Hiroaki, SUGIMOTO, Keiichiro, SHIGEKAWA, Munekazu

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 75 KB

english, 2009

20

Inhibitory effect of aprindine on Na+/Ca2+ exchange current in guinea-pig cardiac ventricular myocytes

Yasuhide Watanabe, Takahiro Iwamoto, Munekazu Shigekawa, Junko Kimura

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 179 KB

english, 2002

21

Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by increasing intracellular pH through serum-independent activation of the Na+/H+ exchanger

Tianxiang Pang, Shigeo Wakabayashi, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 237 KB

english, 2002

22

Second mutations rescue point mutant of the Na+/H+ exchanger NHE1 showing defective surface expression

Shigeo Wakabayashi, Tianxiang Pang, Xiaohua Su, Munekazu Shigekawa

Journal:

Year:

2000

Language:

english

File:

PDF, 426 KB

english, 2000

23

Evidence for Involvement of the Putative First Extracellular Loop in Differential Volume Sensitivity of the Na + /H + Exchangers NHE1 and NHE2 †

Su, Xiaohua, Pang, Tianxiang, Wakabayashi, Shigeo, Shigekawa, Munekazu

Journal:

Year:

2003

Language:

english

File:

PDF, 263 KB

english, 2003

24

Cardioprotective Effects of 9-Hydroxyellipticine on Ischemia and Reperfusion in Isolated Rat Heart

Saeki, Kazuhiko, Obi, Ichiro, Ogiku, Noriko, Shigekawa, Munekazu, Imagawa, Toshiaki, Matsumoto, Takeshi

Journal:

The Japanese Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 263 KB

english, 2002

25

Activation of Actomyosin-ATPase by Tropomyosin*

SHIGEKAWA, Munekazu, TONOMURA, Yuji

Journal:

Journal of Biochemistry

Year:

1972

Language:

english

File:

PDF, 234 KB

english, 1972

26

The phosphorylation and inhibition of Na+/Ca2+ exchanger in phenylephrin-treated hypertrophic cardiomyocytes

Yuki Katanosaka, Yuko Iwata, Shigeo Wakabayashi, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

27

Expression of Ca2+-induced Ca2+ release channel activity from cardiac ryanodine receptor cDNA in Chinese hamster ovary cells

Toshiaki Imagawa, Junichi Nakai, Hiroshi Takeshima, Shosaku Numa, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 89 KB

english, 1992

28

Molecular mechanism of sarcoplasmic reticulum calcium pump

Munekazu Shigekawa, Tarou Ogurusu, Shigeo Wakabayashi

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 82 KB

english, 1992

29

Isolation and characterization of myotubes from bio 14.6 hamsters

Yuki Katanosaka, Murilio Sampaolesi, Yuko Iwata, Zhu Shijun, Hironori Hanada, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 134 KB

english, 2001

30

Inhibitory Effects of Water-Soluble Low-Molecular-Weight β-(1,3-1,6) D -Glucan Isolated from Aureobasidium pullulans 1A1 Strain Black Yeast on Mast Cell Degranulation and Passive Cutaneous Anaphylaxis

SATO, Harumi, KOBAYASHI, Yuko, HATTORI, Atsushi, SUZUKI, Toshio, SHIGEKAWA, Munekazu, JIPPO, Tomoko

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2012

Language:

english

File:

PDF, 189 KB

english, 2012

31

Pathophysiological roles of Ca 2+ overload via the Na + /Ca 2+ exchanger and endothelin-1 overproduction in ischaemia/reperfusion-induced acute renal failure

MATSUMURA, Yasuo, YAMASHITA, Junji, KITA, Satomi, IWAMOTO, Takahiro, OGATA, Masaya, TAKAOKA, Masanori, WAKIMOTO, Koji, SHIGEKAWA, Munekazu, KOMURO, Issei

Journal:

Clinical Science

Year:

2002

Language:

english

File:

PDF, 81 KB

english, 2002

32

Physiological functions of endoplasmic and sarcoplasmic reticulum Ca pump and pharmacology of inhibitors of the pump.

WATANABE, Minoru, SHIGEKAWA, Munekazu

Journal:

Folia Pharmacologica Japonica

Year:

1993

File:

PDF, 21.67 MB

1993

33

Detachment of Cultured Cells from the Substratum Induced by the Neutrophil-Derived Oxidant NH2Cl: Synergistic Role of Phosphotyrosine and Intracellular Ca2+Concentration

Tomoe Y. Nakamura, Itaru Yamamoto, Hideo Nishitani, Takashi Matozaki, Toshiya Suzuki, Shigeo Wakabayashi, Munekazu Shigekawa and Kiyota Goshima

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 2.34 MB

english, 1995

34

Regulation of the Na + /H + exchanger in fibroblasts overexpressing the Na + /Ca 2+ exchanger

Ikeda, Toshitaro, Iwamoto, Takahiro, Wakabayashi, Shigeo, Shigekawa, Munekazu

Journal:

American journal of physiology. Cell physiology

Year:

1998

Language:

english

File:

PDF, 183 KB

english, 1998

35

Stretch-induced cell damage in sarcoglycan-deficient myotubes

Maurilio Sampaolesi, Tomokazu Yoshida, Yuko Iwata, Hironori Hanada, Munekazu Shigekawa

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 224 KB

english, 2001

36

Phosphorylation of Na+/Ca2+ Exchanger in TAB-Induced Cardiac Hypertrophy

YUKI KATANOSAKA, BONGJU KIM, SHIGEO WAKABAYASHI, SATOSHI MATSUOKA, MUNEKAZU SHIGEKAWA

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 77 KB

english, 2007

37

Na+/Ca2+ exchanger overexpression impairs calcium signaling in fibroblasts: Inhibition of the [Ca2+] increase at the cell periphery and retardation of cell adhesion

Takahiro Iwamoto, Shigeo Wakabayashi, Toshiaki Imagawa, Munekazu Shigekawa

Journal:

European Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 3.59 MB

english, 1998

38

Abnormal calcium homeostasis and cell damage in dystrophic myotubes

Yuko Iwata, Maurilio Sampaolesi, Yuke Katanosaka, Zhu Shijun, Hironori Hanada, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 137 KB

english, 2001

39

S2-2 Cardiac Na+Ca2+ exchanger is regulated by calcineurin

Yuki Katanosaka, Takahiro Iwamoto, Futoshi Shibazaki, Yuko Iwata, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 193 KB

english, 2002

40

Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells

Yuko Iwata, Yuki Katanosaka, Zhu Shijun, Yuko Kobayashi, Hironori Hanada, Munekazu Shigekawa, Shigeo Wakabayashi

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 501 KB

english, 2005

41

Maxi K+channels are stimulated by cyclic guanosine monophosphate-dependent protein kinase in canine coronary artery smooth muscle cells

Junichi Taniguchi, Ken -Ichi Furukawa, Munekazu Shigekawa

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1993

Language:

english

File:

PDF, 661 KB

english, 1993

42

Cyclic AMP Enhances Inositol Trisphosphate-Induced Mobilization of Intracellular Ca2+ in Cultured Aortic Smooth Muscle Cells1

Tawada, Yuko, Furukawa, Ken-Ichi, Shigekawa, Munekazu

Journal:

Journal of Biochemistry

Year:

1988

Language:

english

File:

PDF, 702 KB

english, 1988

43

Time-dependent changes of calcium influx and efflux rates in rabbit skeletal muscle sarcoplasmic reticulum

Arnold M. Katz, Charles F. Louis, Doris I. Repke, Gary Fudyma, Priscilla A. Nash-Adler, Robert Kupsaw, Munekazu Shigekawa

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1980

Language:

english

File:

PDF, 899 KB

english, 1980

44

Membrane abnormality in Bio14.6 cardiomyopathic hamster heart

Yuko Iwata, Taro Ogurusu, Toshiaki Imagawa, Hiroshi Nakamura, Munekazu Shigekawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 101 KB

english, 1992

45

Polymorphism of Na+/Ca2+ exchanger gene and antihypertensive response to calcium channel blockers in patients with essential hypertension

Masayoshi Yoshii, Shin Takiuchi, Kei Kamide, Yoshikazu Miwa, Tetsutaro Matayoshi, Yoichi Takami, Takeshi Horio, Chihiro Tanaka, Mariko Banno, Takahiro Iwamoto, Munekazu Shigekawa, Toshiyuki Miyata, Yu

Journal:

American Journal of Hypertension

Year:

2003

Language:

english

File:

PDF, 38 KB

english, 2003

46

Some kinetic properties of phosphorylated ATPase of sarcoplasmic reticulum formed in the absence of added alkali metal salts

Munekazu Shigekawa, Joseph P. Dougherty

Journal:

Biochemical and Biophysical Research Communications

Year:

1977

Language:

english

File:

PDF, 307 KB

english, 1977

47

Phosphorylation-dependent Regulation of Cardiac Na + /Ca 2+ Exchanger via Protein Kinase C

Iwamoto, Takahiro, Pan, Yan, Wakabayashi, Shigeo, Imagawa, Toshiaki, Yamanaka, Hachiro I., Shigekawa, Munekazu

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 606 KB

english, 1996

48

A mechanism of Ca2+ release from Ca2+ stores coupling to the Na+/Ca2+ exchanger in cultured smooth muscle cells

Takashi Hisamitsu, Hisayuki Ohata, Toru Kawanishi, Takahiro Iwamoto, Munekazu Shigekawa, Hitoshi Amano, Shoji Yamada, Kazutaka Momose

Journal:

Year:

2001

Language:

english

File:

PDF, 296 KB

english, 2001

49

Generation of Cell Transfectants Expressing Cardiac Calcium Ion Channel and Calcium Indicator Protein Aequorin

Akito Maeda, Seiichiro Nishimura, Kinu Kameda, Toshiaki Imagawa, Munekazu Shigekawa, Edward Leon Barsoumian

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 150 KB

english, 1996

50

Structure-function of the Na+/H+ exchangers: Role of interacting proteins

Wakabayashi, Shigeo, Pang, Tianxiang, Su, Xiaohua, Shigekawa, Munekazu

Journal:

Kidney International

Year:

2001

Language:

english

File:

PDF, 303 KB

english, 2001

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